Pregnancy-Induced Remodelling of Heart Valves

Pregnancy Outcome with Intracytoplasmic Sperm Injection Method in a Woman with Prosthetic Heart Valves

There is an increased risk of thromboembolism, anticoagulant-related hemorrhage, fetal-wastage and congestive cardiac failure in pregnant women with mechanical heart valves. In order to have a good outcome, the care of such patients must necessarily be multidisciplinary and in a well- equipped centre with adequate support services .One such patient who had mechanical mitral and aortic valves re...

Anti-Coagulation During Pregnancy in Women with Mechanical Heart Valves: A Prospective Study

Pregnancy-induced remodeling of heart valves.

Recent studies have demonstrated remodeling of aortic and mitral valves leaflets under the volume loading and cardiac expansion of pregnancy. Those valves' leaflets enlarge with altered collagen fiber architecture, content, and cross-linking and biphasic changes (decreases, then increases) in extensibility during gestation. This study extends our analyses to right-sided valves, with additional ...

Outcome of pregnancy in women with valve prostheses.

OBJECTIVE To study the outcome of pregnancy in women with artificial heart valves treated in major European centres, and to compare the safety and efficacy of different anticoagulant regimens and of mechanical and bioprosthetic valves. DESIGN Retrospective study. METHOD The information was obtained by questionnaire sent to all major cardiac centres in Europe sending one cardiologist from ea...

Anti-Coagulation During Pregnancy in Women with Mechanical Heart Valves: A Prospective Study

BACKGROUND Pregnancy is associated with a hypercoagulable state, therefore the optimal anticoagulants for potential use in pregnant women with prosthetic heart valves are controversial. The aim of this study is to investigate the effect of anticoagulants on pregnancy outcomes and their potential risks in pregnant women with mechanical heart valves. MATERIALS AND METHODS In this prospective co...